MHI Seminar Series presents John W. Elrod, Ph.D., Director, Cardiovascular Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA
Summary of Seminar: Dr. Elrod’s Lab recently reported that glutaminolysis is essential for the epigenetic changes permissive to activation of the myofibroblast differentiation program and cardiac fibrosis. In fact, targeting these pathways is sufficient to reverse fibrosis in models of heart failure. These findings implicate metabolic remodeling as a critical feature of myofibroblast formation and … Read more