UNC School of Medicine scientists led the largest-ever genomic study of postpartum depression showing genetic correlations between PPD and other psychiatric conditions, as well as providing potential evidence of how the only FDA-approved treatment for PPD works.

This RTI/UNC-Chapel Hill collaboration will be the first U.S. study offering genome sequencing and genetic risk scores for type 1 diabetes statewide. UNC School of Medicine leads are Cynthia Powell, MD, in genetics and pediatrics, and Jennifer Law, MD, in pediatrics.

Led by Hyejung Won, PhD, UNC School of Medicine researchers and colleagues developed a new research model to glean a deeper understanding of the genetic variants implicated in schizophrenia, including how genes are turned on or off to affect health and disease.

Jane Little, MD, and Maria Boucher, MD, both in the UNC School of Medicine, detail the current struggles of patients with sickle cell disease and how we can help.

UNC School of Medicine researchers Christopher Sayed, MD, Yun Li, PhD, and Karen Mohlke, PhD, discovered the genomic locations that contribute to the genetic risk of a chronic skin condition.

UNC School of Medicine’s Patrick Sullivan, MD, FRANZCP, and a team of scientists in the Psychiatric Genetic Consortium have created a new manual researchers can use to learn more about the origins of human diseases with high genetic risk.

Keriayn Smith, PhD, receives $665,786 over the course of four years to research non-coding RNA in yeast, mammalian cells, and more.

Led by Jin Szatkiewicz, PhD, UNC School of Medicine researchers and University of Toronto colleagues found that a rare form of a common genetic variant called tandem repeats is strongly associated with the development of schizophrenia.

Keriayn Smith, PhD, assistant professor in the Department of Genetics, was selected as one of six inaugural recipients of grants from the Hypothesis Fund to advance early-stage innovative research.

UNC Lineberger's Chad V. Pecot, MD, published a paper that found inflammatory monocytes, immune cells that build clots to promote wound healing, also make it possible for tumor cells to migrate to other parts of the body.

Chad Pecot, MD, associate professor of medicine and member of the UNC Lineberger Comprehensive Cancer Center, will lead the new center dedicated to the investigation of the many roles of RNA in health and disease.

UNC School of Medicine researchers led by Hyejung Won, PhD, used a new kind of computational tool to parse the complicated genetics that put some people at higher risk of becoming addicted to alcohol, cigarettes, and likely other substances of abuse.

Enabling or inhibiting the capsase-7 enzyme could trigger the body’s natural immune response, according to a paper published in Nature from scientists at Duke, UNC-Chapel Hill, and UVA.

Tag: Genetics

Researchers Confirm Postpartum Depression Heritability, Home in on Treatment Mechanism

Early Check Study to Use Genome Sequencing to Dramatically Expand Voluntary Screening Offered for NC Newborns

Scientists Take Next Big Step in Understanding Genetics of Schizophrenia

Sickle Cell Disease Continues to Face Underfunding, Lack of Research

Researchers Discover Genetic Locations for Increased Risk of Hidradenitis Suppurativa

Mammalian Evolution Provides Hints for Understanding the Origins of Human Disease

Smith Earns NSF Grant to Study “Dark Matter” of the Genome

Scientists Link Rare Genetic Phenomenon to Neuron Function, Schizophrenia

Smith Selected as Hypothesis Fund Seed Grant Recipient

UNC Lineberger Creates RNA Discovery Center

Scientists Reveal Genetic Architecture Underlying Alcohol, Cigarette Abuse

Scientists Reveal Function of Cell Death Enzyme Capsase-7