This data resource will provide physicians and researchers with new capabilities to identify patterns, support clinical decisions, and accelerate research aimed at transforming rare disease diagnosis and care.

Backed by results from the OPTIMA trial, the Prosigna Breast Risk of Recurrence (ROR) test offers a new way to personalize treatment and reduce unnecessary chemotherapy for patients with breast cancer.

The genetic tool allows doctors to better tailor treatments to each patient's unique subtype of B-cell acute lymphoblastic leukemia.

Backed by new research findings, researchers at the UNC School of Medicine have developed a new reporting system that will allow researchers across the United States to confirm the genetic accuracy of their mouse models.

In a new paper, researchers propose treating health data as essential national infrastructure, balancing patient empowerment, privacy, innovation, and public good.

A geneticist at the UNC School of Medicine has coordinated the development of Mondo, the world’s first standardized rare disease coding tool. Mondo is designed to streamline the diagnosis and treatment planning for millions of patients with rare diseases internationally.

A new study in the lab of Jason Stein, PhD, modeled brain development in a dish to identify cells and genes that influence infant brain growth, a trait associated with autism.

Laura Klinger, PhD, of psychiatry, and Jason Stein, PhD, in genetics, together with Joseph Piven, MD, in psychiatry, received two $4 million grants to study the root causes and improve therapies to help autistic people live happier and healthier lives.

A decade after winning the Nobel Prize, the UNC professor continues to push the boundaries of discovery while inspiring the next generation and building cultural bridges between the United States and Türkiye.

Each year, the Postdoctoral Awards for Research Excellence (PARE) are given in recognition of the research promise demonstrated by individual postdoctoral scholars.

In a surprising twist, UNC scientists discovered that SETD2, a tumor suppressor, also preserves nuclear structure during cell division—a hidden role that may explain its tumor-suppressive effects in cancer.

New knowledge of these protein functions will help researchers develop new drug targets for chronic pain, autism spectrum disorders, epilepsy, migraines, and other neurological conditions.

Tag: Genetics

UNC Awarded Up to $35 Million to Lead Landmark Initiative to Build World’s Largest Data Resource for Rare Disease AI

Hormone Therapy or Chemotherapy? A Test Developed by a UNC Researcher Can Tell You

UNC Researchers Develop Faster, Low-Cost Method to Diagnose Common Pediatric Cancer

UNC Launches New Tool to Ensure Accuracy, Rigor of Mouse-based Biomedical Research

UNC Researchers Call for Governing Health Data as a Public Utility to Unlock Real-World Evidence and Protect Patients

UNC Health Launches Revolutionary Coding Standard to Transform Rare Disease Diagnosis Nationwide

UNC Researchers Build Stem Cell Models to Mimic Early Brain Development

UNC School of Medicine Secures Two Major NIH Grants for Autism Research

The Enduring Legacy of Dr. Aziz Sancar

UNC Research Announces 2025 PARE Award Recipients

UNC Scientists Uncover Hidden Role of Tumor Suppressor Gene in Protecting the Genome

Proteins Important in Neural Communication Have Different Roles Than Previously Thought