Drug work one of “7 Medical Breakthroughs that Changed Medicine in 2024.”

Yamini Virkud, MD, MPH, associate professor of pediatrics and director of Bioinformatics at the UNC FAI in the Department of Pediatrics at the UNC School of Medicine

New research led by Yamini Virkud, MD, MPH, associate professor of pediatrics, director of Bioinformatics at the UNC Food Allergy Initiative (FAI) in the Department of Pediatrics at the UNC School of Medicine, reveals key metabolite pathways associated with food allergy and differential responses to oral immunotherapy to treat food allergy.

A research project co-led by James Hagood, MD, professor of pediatrics at the UNC School of Medicine, and colleagues will be supported in creating an atlas of the cells and cellular interactions in the nasal and oral cavities, throat, and lower airways of pediatric populations in unprecedented detail.

The Patient-Centered Outcomes Research Institute (PCORI) announced funding totaling $14.4 million for a Duke-UNC research collaboration to study new treatment options for pediatric inflammatory bowel diseases (PIBD). Michael D. Kappelman, MD, MPH, professor of pediatrics and epidemiology at the UNC School of Medicine, will serve as principal investigator.

A comprehensive analysis published in the journal Gastroenterology and led by Michael D. Kappelman, MD, MPH, at the UNC School of Medicine, reveals that U.S. pediatric IBD rates have increased, ranking among the highest globally.

Edwin Kim, MD MS, director of the UNC Food Allergy Initiative at the UNC School of Medicine, will lead the first study of sublingual immunotherapy to address the feasibility and safety of treating multiple tree nut allergens simultaneously in children.

A large study co-led by Kori Flower, MD, MS, MPH, division chief of General Pediatrics and Adolescent Medicine at the UNC School of Medicine demonstrates that combining text messaging with in-person clinic counseling reduces obesity in the first two years of life. Samantha Schilling, MD, MSHP, associate professor in the Division of General Pediatrics and Adolescent Medicine at UNC, was also a co-investigator in the study.

UNC Children's has opened the Muenzer MPS Research and Treatment Center dedicated to improving the lives of patients with mucopolysaccharidoses (MPS), a group of rare inherited conditions, and advancing research with the goal of creating better therapies.

The lab of Graham Diering, PhD, assistant professor of cell biology and physiology at the UNC School of Medicine, shows how sleep loss during early life impacts key aspects of brain development and how it can increase one’s risk for developing autism spectrum disorder.

Nina Jain, MD, MBA, professor of pediatric endocrinology, and Ali Calikoglu, MD, retired professor of pediatrics, both at the UNC School of Medicine, played a pivotal role in getting this therapy to the bedside, from assisting with clinical trials to the infusion of the first pediatric patient in North Carolina at UNC Children’s.

Publishing in Annals of Allergy, Asthma and Immunology, UNC School of Medicine researchers delve into the perspectives of community and academic providers on the role of biologics and food allergy. This study was led by co-authors Edwin Kim, MD, Division Chief of Pediatric Allergy and Immunology, and Jill Fisher, PhD, professor in the UNC Department of Social Medicine and Center for Bioethics.

In May 2022, Yael Shiloh-Malawsky, MD, a neurologist at the UNC School of Medicine, met two new patients combatting a rare and fatal neurodegenerative disorder called Batten disease. With help from UNC, the twin girls were able to get personalized treatment from bench to bedside in record time.

Tag: Pediatrics

UNC ‘Breakthrough’ Research on Food Allergy Drug Featured in National Geographic

Study Reveals Importance of Bile Acids and other Metabolites in Food Allergies and Treatment

UNC Researchers to Accelerate Mapping of Cells Crucial to Child Respiratory Health and Disease

PCORI Awards UNC Researcher $14.4 Million to Study Emerging Medications for PIBD Patients

Kappelman Leads Landmark Study Revealing That 100,000 American Youth Are Living with Inflammatory Bowel Disease

Kim Receives $1-Million Grant for Novel Multi-nut Allergy Treatment Study

New Study Finds Obesity Can Be Prevented in Very Young Children

UNC Children’s Opens Muenzer MPS Center in Chapel Hill

Let Sleeping Babies Lie: Scientists Highlight Negative Impacts of Sleep Disruption on Early Brain Development

A New Therapy to Prevent or Delay Type 1 Diabetes Now Available at UNC Children’s Hospital

Are Biologics the Future of Food Allergy Treatment? One Study Weighs Pros and Cons

UNC Fast-Tracks Personalized Treatment for Twins with Ultra Rare Genetic Disorder