Press Releases

Scientists discover new gene expression mechanism with possible role in human disease

Scientists discover new gene expression mechanism with possible role in human disease

UNC School of Medicine researchers, led by Brian Strahl, PhD, found surprising role for a protein called Spt6, which is crucial to the maintenance of proper messenger RNA levels in cells, a discovery that opens new research avenues and suggests a target for basic understanding, diagnosis, and treatment of human diseases.

Scientists discover new gene expression mechanism with possible role in human disease - Read More…

UNC study: Tdap vaccine given during pregnancy reduces occurrence of infant pertussis

UNC study: Tdap vaccine given during pregnancy reduces occurrence of infant pertussis

A study led by UNC’s Sylvia Becker-Dreps, MD, MPH, reviewed more than 675,000 pregnancies in the U.S. to determine if the Tdap vaccine given to a mother will reduce the chances of her child developing pertussis during the first 18 months of life. The results show a decrease in overall cases of pertussis, and most notably, in pertussis hospitalization in infants whose mothers were immunized during pregnancy.

UNC study: Tdap vaccine given during pregnancy reduces occurrence of infant pertussis - Read More…

UNC Medical Center receives two Mission: Lifeline awards from American Heart Association

UNC Medical Center receives two Mission: Lifeline awards from American Heart Association

Both awards recognize the implementation of specific quality improvement measures for the treatment of patients who suffer severe heart attacks.

UNC Medical Center receives two Mission: Lifeline awards from American Heart Association - Read More…

The Measure of a Doctor

The Measure of a Doctor

As Harold Pillsbury, MD, retires as chair of UNC Otolaryngology/ Head and Neck Surgery, we take a look back at his career through the eyes of one of his patients.

The Measure of a Doctor - Read More…

UNC Health Care CEO, Medical School Dean Bill Roper Plans to Step Down in 2019

UNC Health Care CEO, Medical School Dean Bill Roper Plans to Step Down in 2019

Dr. Roper led expansion efforts in education, research, and clinical care that improved health for all North Carolinians.

UNC Health Care CEO, Medical School Dean Bill Roper Plans to Step Down in 2019 - Read More…

Genetic Testing for Statin Therapy Not Cost-Effective

Genetic Testing for Statin Therapy Not Cost-Effective

Research led by UNC School of Medicine MD/PhD student Jamie Jarmul, PhD, suggests physicians should defer to traditional 10-year risk score and existing statin guidelines in lieu of genetic tests.

Genetic Testing for Statin Therapy Not Cost-Effective - Read More…

UNC AFib Care Network Launches AFib Integrated Care Clinic

UNC AFib Care Network Launches AFib Integrated Care Clinic

Network also launches AFib support group and a smartphone app to help people with AFib manage their condition

UNC AFib Care Network Launches AFib Integrated Care Clinic - Read More…

Arrival of Three Mannequins Will Increase High-Fidelity Patient Simulations

Arrival of Three Mannequins Will Increase High-Fidelity Patient Simulations

The School of Medicine’s Clinical Skills and Patient Simulation Center has three new mannequins to facilitate simulations for students. This is the first purchase of a mannequin in nearly a decade and provides a new educational tool that reinforces UNC’s standard of safety.

Arrival of Three Mannequins Will Increase High-Fidelity Patient Simulations - Read More…

UNC researchers discover how body temperature wrecks potential dengue, Zika vaccine

UNC researchers discover how body temperature wrecks potential dengue, Zika vaccine

The UNC School of Medicine labs of Brian Kuhlman, PhD, and Aravinda de Silva, PhD, found that key components of a potentially potent vaccine fall apart due to body temperature, leaving us susceptible to severe infection.

UNC researchers discover how body temperature wrecks potential dengue, Zika vaccine - Read More…

UNC researchers present study about family history and postpartum mental health at national APA Conference

UNC researchers present study about family history and postpartum mental health at national APA Conference

Anna Bauer, PhD, and Samantha Meltzer-Brody, MD, MPH, were chosen by the APA to present findings from their recently published study about a new mother’s risk of postpartum psychiatric conditions when she has an immediate family member with a psychiatric disorder.

UNC researchers present study about family history and postpartum mental health at national APA Conference - Read More…

Phenotyping may lead to more tailored treatment for head and neck cancer

Phenotyping may lead to more tailored treatment for head and neck cancer

Fourth-year medical student Wesley Stepp, PhD, has developed a testing method to predict aggressiveness of head and neck cancers and help physicians determine the ideal treatment regimen.

Phenotyping may lead to more tailored treatment for head and neck cancer - Read More…

NC TraCS and partners awarded $58.1 million to accelerate research discoveries

NC TraCS and partners awarded $58.1 million to accelerate research discoveries

The NIH award features a new partnership with NC State, while the UNC-Chapel Hill-led Clinical and Translational Science Award Program continues its alliance with RTI International and N.C. A&T State University.

NC TraCS and partners awarded $58.1 million to accelerate research discoveries - Read More…

Male Contraceptive Compound Stops Sperm Without Affecting Hormones

Male Contraceptive Compound Stops Sperm Without Affecting Hormones

In preclinical tests, researchers from UNC-Chapel Hill and Oregon Health and Sciences University showed how a new compound can immobilize sperm temporarily without side effects.

Male Contraceptive Compound Stops Sperm Without Affecting Hormones - Read More…

How Does Plant DNA Avoid the Ravages of UV Radiation?

How Does Plant DNA Avoid the Ravages of UV Radiation?

The lab of UNC Nobel laureate Aziz Sancar, MD, PhD, reveals first-ever repair map of an entire multicellular organism to illuminate some interesting inner workings of the plant kingdom’s DNA highly efficient repair system.

How Does Plant DNA Avoid the Ravages of UV Radiation? - Read More…

Large Aggregates of ALS-causing Protein Might Actually Help Brain Cells

Large Aggregates of ALS-causing Protein Might Actually Help Brain Cells

UNC School of Medicine scientists led by Nikolay Dokholyan, PhD, add to evidence that small aggregates of SOD1 protein are the brain-cell killing culprits in ALS, but the formation of larger, more visible, and fibril-like aggregates of the same protein may protect brain cells.

Large Aggregates of ALS-causing Protein Might Actually Help Brain Cells - Read More…

UNC Health Care achieves highest rank possible in three health IT categories

UNC Health Care achieves highest rank possible in three health IT categories

UNC Health Care’s Stage 7 designations for hospitals, outpatient practices, and advanced analytics confirm its position as a national leader in health information technology.

UNC Health Care achieves highest rank possible in three health IT categories - Read More…

UNC Aortic Team completes rare total arch aneurysm repair

UNC Aortic Team completes rare total arch aneurysm repair

Mark Farber, MD, and Thomas Caranasos, MD, successfully completed an endovascular total arch aneurysm repair, joining a handful of surgical teams around the world.

UNC Aortic Team completes rare total arch aneurysm repair - Read More…

How did Gonorrhea Become a Drug-resistant Superbug?

How did Gonorrhea Become a Drug-resistant Superbug?

Scientists led by Rob Nicholas, PhD, at the UNC School of Medicine show how the gonorrhea bacterium resists last-resort antibiotic ceftriaxone while maintaining a robust growth rate.

How did Gonorrhea Become a Drug-resistant Superbug? - Read More…

Fragile X Imaging Study Reveals Differences in Infant Brains

Fragile X Imaging Study Reveals Differences in Infant Brains

UNC School of Medicine researchers used MRIs and computer models to show that babies who develop the neurodevelopmental condition fragile X syndrome have less white matter circuitry compared to other babies. About one-third of people with fragile X meet the diagnostic criteria for autism.

Fragile X Imaging Study Reveals Differences in Infant Brains - Read More…

Some e-cigarette ingredients are surprisingly more toxic than others

Some e-cigarette ingredients are surprisingly more toxic than others

UNC School of Medicine scientists led by Robert Tarran created a new screening technique to deduce the different toxicity levels of the more than 7,700 types of e-liquid flavors available to consumers.

Some e-cigarette ingredients are surprisingly more toxic than others - Read More…

Wake Forest Baptist, UNC Health Care Sign Binding Definitive Agreement Regarding Ownership of High Point Regional Health

Over the coming months, leadership from both Wake Forest Baptist and High Point Regional Health will be working together to take the necessary steps toward full integration.

Wake Forest Baptist, UNC Health Care Sign Binding Definitive Agreement Regarding Ownership of High Point Regional Health - Read More…

UNC Researcher Helps Find Solutions for Childcare Conundrum at Academic Conferences

UNC Researcher Helps Find Solutions for Childcare Conundrum at Academic Conferences

Paola Giusti-Rodriguez, PhD, is one of 40 scientists that contributed to a paper outlining the difficulties parents encounter when attending conferences. They offer solutions that could quickly improve attendance and involvement of mothers at these events.

UNC Researcher Helps Find Solutions for Childcare Conundrum at Academic Conferences - Read More…

New therapeutic gel shows promise against cancerous tumors

New therapeutic gel shows promise against cancerous tumors

The lab of Zhen Gu, PhD, in the joint UNC-NC State biomedical engineering department developed a biodegradable hydrogel scaffold system to release chemotherapeutic and immunotherapeutic drugs at the tumor site.

New therapeutic gel shows promise against cancerous tumors - Read More…

Scientists map molecular mechanisms crucial for new approach to heart disease therapy

Scientists map molecular mechanisms crucial for new approach to heart disease therapy

Scientists led by UNC McAllister Heart Institute researcher Frank Conlon, PhD, reveal detailed molecular events underlying the transformation of ordinary fibroblast cells into therapeutic cardiac muscle cells.

Scientists map molecular mechanisms crucial for new approach to heart disease therapy - Read More…

Rodgers to deliver 14th Annual Huntley Lecture

Rodgers to deliver 14th Annual Huntley Lecture

Denise V. Rodgers, MD, FAAFP, Vice Chancellor for Interprofessional Programs at Rutgers Biomedical and Health Sciences, will deliver the 14th Annual Robert R. Huntley, MD Lecture, presented by the Department of Family Medicine. The title of her lecture is "Persistent Health Disparities: Understanding the Role of Social Determinants, Implicit Bias and Racism."

Rodgers to deliver 14th Annual Huntley Lecture - Read More…

Gene therapy researchers find viral barcode to cross the blood-brain barrier

Gene therapy researchers find viral barcode to cross the blood-brain barrier

UNC School of Medicine scientists led by Aravind Asokan, PhD, reveal how certain gene-carrying AAV vectors can penetrate the brain more efficiently to treat brain and spinal cord conditions, while reducing liver payload.

Gene therapy researchers find viral barcode to cross the blood-brain barrier - Read More…

Envisioning His Future

Envisioning His Future

Qing Zhang earns a Jefferson-Pilot Fellowship in Academic Medicine for his work understanding oxygen’s role in therapy-resistant tumors.

Envisioning His Future - Read More…

Kids saying no to cigarettes are saying yes to vaping

Kids saying no to cigarettes are saying yes to vaping

In a study led by UNC Family Medicine’s Adam Goldstein, MD, researchers found that efforts are needed to help youth remain nicotine free – especially those adolescents who aren’t otherwise susceptible to smoking cigarettes.

Kids saying no to cigarettes are saying yes to vaping - Read More…

Scientific Breakthrough Could Lead to Better Antipsychotic Drugs

Scientific Breakthrough Could Lead to Better Antipsychotic Drugs

Published in Nature, research from the lab of Bryan L. Roth, MD, PhD, revealed the first-ever crystal structure of the dopamine 2 receptor bound to an antipsychotic drug – a much-needed discovery in the quest to create effective drugs with fewer side effects to treat bipolar disorder, schizophrenia, and other conditions.

Scientific Breakthrough Could Lead to Better Antipsychotic Drugs - Read More…

Cystic Fibrosis Discovery: Bacterial Burden Begins During First Years of Life

Cystic Fibrosis Discovery: Bacterial Burden Begins During First Years of Life

UNC School of Medicine scientists show that therapies to break up mucus in toddlers might offer the best route to a longer life for CF patients.

Cystic Fibrosis Discovery: Bacterial Burden Begins During First Years of Life - Read More…

 Narrowing the gap toward precision medicine for pancreatic cancer

Narrowing the gap toward precision medicine for pancreatic cancer

To improve treatment and our understanding of one of the deadliest cancers in the United States, UNC Lineberger's Jen Jen Yeh, MD, was involved in two studies that take different approaches to precision medicine for pancreatic cancer.

Narrowing the gap toward precision medicine for pancreatic cancer - Read More…

Nash UNC Health Care Names L. Lee Isley as CEO

Nash UNC Health Care Names L. Lee Isley as CEO

Isley has served as CEO for Granville Health System in Oxford, NC, since 2006, and has held a variety of roles in his 30-year health care career.

Nash UNC Health Care Names L. Lee Isley as CEO - Read More…

Hormone therapy could effectively prevent depression for some women in the menopause transition

Hormone therapy could effectively prevent depression for some women in the menopause transition

Research conducted by Susan Girdler, PhD, and David Rubinow, MD, and published in JAMA Psychiatry, is the first to conclude that a year of hormone therapy can effectively prevent the onset of depressive symptoms for women during the menopause transition.

Hormone therapy could effectively prevent depression for some women in the menopause transition - Read More…

Scientists Take a Big Step toward Building a Better Opioid

Scientists Take a Big Step toward Building a Better Opioid

In a paper published in Cell, UNC School of Medicine researchers led by Bryan Roth, MD, PhD, show how to activate only one kind of brain receptor vital for pain relief. This receptor is not involved in addiction or respiratory depression that leads to death – the most severe side effects of opioid use.

Scientists Take a Big Step toward Building a Better Opioid - Read More…

Nelson named President of Medical Foundation of North Carolina, Associate Dean for Development at the UNC School of Medicine

Nelson named President of Medical Foundation of North Carolina, Associate Dean for Development at the UNC School of Medicine

Leslie H. Nelson has been named as President of the Medical Foundation of North Carolina and Associate Dean for Development of the UNC School of Medicine effective Jan. 1, 2018. The Medical Foundation of North Carolina is the not-for-profit, philanthropic arm of the UNC School of Medicine and UNC Hospitals.

Nelson named President of Medical Foundation of North Carolina, Associate Dean for Development at the UNC School of Medicine - Read More…

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

The lab of Jean Cook, PhD, found how a chain of proteins called an MCM complex could enable the fast cell-division that makes some forms of cancer so dangerous.

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State - Read More…

National Clinical Trial Finds Certain Treatments for Blood Clots Not Effective

National Clinical Trial Finds Certain Treatments for Blood Clots Not Effective

Stephan Moll, MD, professor of medicine and member of the UNC Hemophilia and Thrombosis Center, co-authored the results of a large-scale multicenter clinical trial focusing on catheter-directed thrombolysis and its effects.

National Clinical Trial Finds Certain Treatments for Blood Clots Not Effective - Read More…

Scientists Find Potential Weapons for the Battle Against Antibiotic Resistance

Scientists Find Potential Weapons for the Battle Against Antibiotic Resistance

Led by UNC School of Medicine’s Brian Conlon, PhD, research published in PLoS Biology shows how different bacterial strains interact to make each other more or less resistant to antibiotics.

Scientists Find Potential Weapons for the Battle Against Antibiotic Resistance - Read More…

Inaugural Class of UNC Physician Assistant Program Featured by Blue Cross and Blue Shield of NC

Inaugural Class of UNC Physician Assistant Program Featured by Blue Cross and Blue Shield of NC

An article published on the BCBS website focuses on one upcoming graduate’s experience in the program, her motivation for pursuing a career as a physician assistant, and her goals after graduating this December.

Inaugural Class of UNC Physician Assistant Program Featured by Blue Cross and Blue Shield of NC - Read More…

New simple test could help cystic fibrosis patients find best treatment

New simple test could help cystic fibrosis patients find best treatment

In a significant step toward personalized medicine for cystic fibrosis, a minimally-invasive technique developed in the lab of Martina Gentzsch, PhD, shows promise as a fast, inexpensive indicator to help more patients access new treatments.

New simple test could help cystic fibrosis patients find best treatment - Read More…

Could this Protein Protect People against Coronary Artery Disease?

Could this Protein Protect People against Coronary Artery Disease?

Research led by UNC’s Jonathan Schisler, PhD, showed much lower levels of the protein CXCL5 in older people with clogged arteries.

Could this Protein Protect People against Coronary Artery Disease? - Read More…

A New Test to Measure the Effectiveness of CF Drugs

A New Test to Measure the Effectiveness of CF Drugs

A new lab model developed by UNC’s Carla Ribeiro, PhD, and colleagues can be used to test new therapeutics for cystic fibrosis.

A New Test to Measure the Effectiveness of CF Drugs - Read More…

Fat Cell Gene Deficiency Promotes Obesity

Fat Cell Gene Deficiency Promotes Obesity

UNC School of Medicine’s Damaris Lorenzo, PhD, and colleagues show how a gene variant can trigger obesity in mice – without them eating more than control mice – and lead to health concerns related to weight gain.

Fat Cell Gene Deficiency Promotes Obesity - Read More…

How do adult brain circuits regulate new neuron production?

How do adult brain circuits regulate new neuron production?

In a new study published in Cell Stem Cell, UNC School of Medicine neuroscientist Juan Song and colleagues discovered a long-distance brain circuit that controls the production of new neurons in the hippocampus.

How do adult brain circuits regulate new neuron production? - Read More…

Why do some head knocks cause more damage than others?

Why do some head knocks cause more damage than others?

As researchers piece together puzzling patterns of brain damage after concussions, UNC researchers led by Gianmarco Pinton, PhD, found that damaging shock waves intensified deep inside the brain after head impacts.

Why do some head knocks cause more damage than others? - Read More…

Smart Artificial Beta Cells Could Lead to New Diabetes Treatment

Smart Artificial Beta Cells Could Lead to New Diabetes Treatment

In lab experiments and animal models, UNC and NC State researchers led by Zhen Gu, PhD, designed synthetic beta cells to secrete insulin in response to high blood sugar.

Smart Artificial Beta Cells Could Lead to New Diabetes Treatment - Read More…

How to Turn Damaged Heart Tissue Back into Healthy Heart Muscle: New Details Emerge

How to Turn Damaged Heart Tissue Back into Healthy Heart Muscle: New Details Emerge

Publishing their work in Nature, UNC School of Medicine researchers led by Li Qian, PhD, show how their new research platform helped them discover new cell subpopulations and crucial cellular players in the process of turning damaged heart tissue back into healthy heart muscle. The research platform could be used to study other biological processes and create tailored therapies.

How to Turn Damaged Heart Tissue Back into Healthy Heart Muscle: New Details Emerge - Read More…

UNC Medical Center Offers Innovative Non-surgical Treatment for Enlarged Prostate

UNC Medical Center Offers Innovative Non-surgical Treatment for Enlarged Prostate

Prostatic Artery Embolization (PAE) is a catheter-based procedure to help improve symptoms caused by an enlarged prostate.

UNC Medical Center Offers Innovative Non-surgical Treatment for Enlarged Prostate - Read More…

Key Psychiatric Drug Target Comes Into Focus

Key Psychiatric Drug Target Comes Into Focus

UC San Francisco and UNC-Chapel Hill team solves first ever high-resolution structure of dopamine receptor. Details of the work were published today in Science.

Key Psychiatric Drug Target Comes Into Focus - Read More…

Post Heart Attack: How can scar tissue be turned back into healthy heart muscle?

Post Heart Attack: How can scar tissue be turned back into healthy heart muscle?

For the first time, UNC scientists detail crucial differences in two leading methods for generating heart muscle cells, a key strategy for new post-heart attack therapies.

Post Heart Attack: How can scar tissue be turned back into healthy heart muscle? - Read More…

Graduate science training pays dividends in and out of the lab

Graduate science training pays dividends in and out of the lab

In a study published in PLOS ONE, UNC School of Medicine researchers found that skills developed during science PhD programs translate to success in a wide range of fields.

Graduate science training pays dividends in and out of the lab - Read More…

Faulty cell signaling derails cerebral cortex development, could it lead to autism?

Faulty cell signaling derails cerebral cortex development, could it lead to autism?

UNC School of Medicine researchers pinpoint signaling problems in the progenitor cells crucial for proper neuron generation and organization.

Faulty cell signaling derails cerebral cortex development, could it lead to autism? - Read More…

Chronic Bronchitis: New Insights Could Lead to First Diagnostic Test and Better Treatments

Chronic Bronchitis: New Insights Could Lead to First Diagnostic Test and Better Treatments

A New England Journal of Medicine study describes how airway dehydration makes mucus thick – the hallmark of chronic bronchitis, the precursor to deadly COPD.

Chronic Bronchitis: New Insights Could Lead to First Diagnostic Test and Better Treatments - Read More…

Unraveling Alzheimer’s: New Study Documents How Brain Cells Go Bad

Unraveling Alzheimer’s: New Study Documents How Brain Cells Go Bad

In a first-of-its-kind study, UNC researchers show how a damaging cascade of events inside brain cells – and related to Alzheimer’s disease – can be stopped or reversed.

Unraveling Alzheimer’s: New Study Documents How Brain Cells Go Bad - Read More…

UNC Health Care CEO William Roper Named to Modern Healthcare’s 100 Most Influential People in Healthcare

UNC Health Care CEO William Roper Named to Modern Healthcare’s 100 Most Influential People in Healthcare

As UNC Health Care’s CEO, Dr. Roper oversees a clinical enterprise that provides more than 3 million clinic visits across North Carolina each year. He is also Dean of the UNC School of Medicine, which is nationally ranked for primary care, family care and rural medicine.

UNC Health Care CEO William Roper Named to Modern Healthcare’s 100 Most Influential People in Healthcare - Read More…

Scientists create stem cell therapy for lung fibrosis conditions

Scientists create stem cell therapy for lung fibrosis conditions

Through a joint UNC School of Medicine-NC State research project shows how to harvest lung stem cells non-invasively and then multiply healthy cells – a potential powerful therapy against inflammatory lung conditions.

Scientists create stem cell therapy for lung fibrosis conditions - Read More…

UNC teams with Verily Life Sciences to study trauma recovery

UNC teams with Verily Life Sciences to study trauma recovery

The Verily Study Watch will help researchers at the UNC School of Medicine and across the country collect first-in-kind data to better understand and diagnose adverse brain outcomes after trauma.

UNC teams with Verily Life Sciences to study trauma recovery - Read More…

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease

UNC and NC State researchers team up to reverse TDP-43 protein aggregation, a hallmark of degenerative diseases.

ALS: New Clues to the Cause and How Future Drugs Might Reverse Disease - Read More…

Toddler Brain Development: bacterial clues found in dirty baby diapers

Toddler Brain Development: bacterial clues found in dirty baby diapers

Can the kinds of microbes colonizing the gut at age 1 predict later cognitive development? Findings from the UNC School of Medicine shed light on the surprising role of bacteria in how our brains develop during the first years of life.

Toddler Brain Development: bacterial clues found in dirty baby diapers - Read More…

A new resource for Alzheimer’s and dementia caregivers

A new resource for Alzheimer’s and dementia caregivers

Longtime UNC family medicine researcher Philip Sloane, MD, MPH, wrote a book that employs the latest clinical evidence to help those caring for someone with Alzheimer’s disease or dementia.

A new resource for Alzheimer’s and dementia caregivers - Read More…

UNC Health Care honored as 'Most Wired Advanced'

UNC Health Care honored as 'Most Wired Advanced'

UNC Health Care is one of only 27 systems in the United States to be recognized as a 'Most Wired Advanced’ health system by the American Hospital Association (AHA) for its use of information technology to improve patient care and clinical integration.

UNC Health Care honored as 'Most Wired Advanced' - Read More…

Teen ACL injuries on the rise, UNC researchers call for wider use of injury prevention programs

Teen ACL injuries on the rise, UNC researchers call for wider use of injury prevention programs

New research from UNC shows that rates of anterior cruciate ligament (ACL) reconstruction are increasing sharply, with the most dramatic increase among girls aged 13-17.

Teen ACL injuries on the rise, UNC researchers call for wider use of injury prevention programs - Read More…

Kenan Charitable Trust Awards $1.5 million to UNC Health Affairs Schools

Kenan Charitable Trust Awards $1.5 million to UNC Health Affairs Schools

The William R. Kenan, Jr. Charitable Trust has awarded the UNC School of Medicine $1.5 million to establish interprofessional clinical experiences for health professions students in rural areas of the state, launching the UNC Rural Interprofessional Health Initiative (RIPHI).

Kenan Charitable Trust Awards $1.5 million to UNC Health Affairs Schools - Read More…

Pregnant women should be included in Zika virus vaccine research, new guidance says

Pregnant women should be included in Zika virus vaccine research, new guidance says

The inclusion of pregnant women in Zika virus vaccine research is crucial to solving the international health crisis, according to new guidance published by UNC’s Center for Bioethics and two other universities.

Pregnant women should be included in Zika virus vaccine research, new guidance says - Read More…

How blood vessels control their destiny

How blood vessels control their destiny

UNC researchers define the importance of the decoy receptor VEGFR1 in the process of angiogenesis, in findings that could have important implications in the treatment of cancer and other diseases.

How blood vessels control their destiny - Read More…

 Using ‘sticky’ nanoparticles, researchers develop new strategy to boost body’s cancer defenses

Using ‘sticky’ nanoparticles, researchers develop new strategy to boost body’s cancer defenses

In the journal Nature Nanotechnology, UNC Lineberger researchers led by Andrew Wang, MD, report on strides made in the development of a strategy to improve the immune system's detection of cancer proteins by using “sticky” nanoparticles.

Using ‘sticky’ nanoparticles, researchers develop new strategy to boost body’s cancer defenses - Read More…

UNC bioethicist pens ‘cautionary tale’ for Zika vaccine development and pregnancy

UNC bioethicist pens ‘cautionary tale’ for Zika vaccine development and pregnancy

UNC’s Anne Lyerly, MD, published an opinion piece in JAMA Pediatrics that urges scientists to use lessons learned during the Rubella outbreak as they work to develop a vaccine for the Zika virus, specifically as it relates to the ethics of including pregnant women in vaccine trials.

UNC bioethicist pens ‘cautionary tale’ for Zika vaccine development and pregnancy - Read More…

Newly designed viral vectors could lead to improved gene therapies

Newly designed viral vectors could lead to improved gene therapies

UNC and University of Florida researchers created viruses to deliver gene therapies while evading pre-existing immune system responses. Aravind Asokan, PhD, led the research team at UNC.

Newly designed viral vectors could lead to improved gene therapies - Read More…

UNC/NC State spinout company raises $5.8M for ‘smart’ insulin devices

UNC/NC State spinout company raises $5.8M for ‘smart’ insulin devices

A Research Triangle Park startup founded by Zhen Gu, PhD, a biomedical engineer with joint faculty appointments at UNC and NC State University received a $5.8 million cash infusion to continue translation efforts of ‘smart’ insulin devices.

UNC/NC State spinout company raises $5.8M for ‘smart’ insulin devices - Read More…

UNC co-leads large clinical trial on new combo therapy for type 2 diabetes

UNC co-leads large clinical trial on new combo therapy for type 2 diabetes

New insulin degludec has comparable cardiovascular safety rates to insulin glargine U100 but with less risk of triggering low blood sugar.

UNC co-leads large clinical trial on new combo therapy for type 2 diabetes - Read More…

Researchers strive to improve cancer care for older patients

Researchers strive to improve cancer care for older patients

At the 2017 American Society of Clinical Oncology Annual Meeting in Chicago, UNC Lineberger researchers led by Hyman B. Muss, MD, presented preliminary findings from several studies focused on older adults with cancer.

Researchers strive to improve cancer care for older patients - Read More…

Researchers show how a cancer gene protects genome organization

Researchers show how a cancer gene protects genome organization

UNC study uncovers crucial function of a yeast enzyme Set2 whose well-conserved human counterpart is often mutated in cancers, especially kidney cancer.

Researchers show how a cancer gene protects genome organization - Read More…

Where Cigarette Smoking’s Damage is Done . . . Down to Your DNA

Where Cigarette Smoking’s Damage is Done . . . Down to Your DNA

A new technique from UNC School of Medicine scientists led by Nobel Prize winner Aziz Sancar reveals the genome-wide DNA damage that a major carcinogen causes.

Where Cigarette Smoking’s Damage is Done . . . Down to Your DNA - Read More…

Is the finger-stick blood test necessary for type 2 diabetes treatment?

Is the finger-stick blood test necessary for type 2 diabetes treatment?

In the first large pragmatic trial of its kind in the United States, results from a UNC School of Medicine study show that checking finger-stick blood sugars may not help diabetes patients who do not use insulin.

Is the finger-stick blood test necessary for type 2 diabetes treatment? - Read More…

UNC researchers lead clinical trial evaluating potential treatment for postpartum depression

UNC researchers lead clinical trial evaluating potential treatment for postpartum depression

A phase 2, double-blind study of the investigational medication, brexanolone, in the treatment of women with severe PPD published in The Lancet. Clinical trials are currently underway at UNC.

UNC researchers lead clinical trial evaluating potential treatment for postpartum depression - Read More…

Predicting Autism: Study Links Infant Brain Connections to Diagnoses at Age 2

Predicting Autism: Study Links Infant Brain Connections to Diagnoses at Age 2

In two previous studies, University of North Carolina researchers and colleagues linked infant brain anatomy differences to autism diagnoses at age two. Now they show differences in functional connections between brain regions at 6 months to predict autism at age two.

Predicting Autism: Study Links Infant Brain Connections to Diagnoses at Age 2 - Read More…

Promising results found for treatment of melanoma in the brain

Promising results found for treatment of melanoma in the brain

At the American Society of Clinical Oncology Annual Meeting 2017 in Chicago, researchers presented promising data for two different investigational drug regimens used to treat melanoma that has spread to the brain, a common and deadly complication of this cancer.

Promising results found for treatment of melanoma in the brain - Read More…

New models of kidney cancer may drive immunotherapy research

New models of kidney cancer may drive immunotherapy research

UNC Lineberger member William Y. Kim, MD, and his colleagues report in the journal Nature Communications they have created mouse models of both papillary and clear cell renal cell carcinoma that faithfully mimic the genetic changes seen in tumors of patients with these cancers.

New models of kidney cancer may drive immunotherapy research - Read More…

 With ‘new life’ after transplant, cancer survivor renews marriage vows

With ‘new life’ after transplant, cancer survivor renews marriage vows

Recognizing that her husband now had a chance for a new, healthier life thanks to a stem cell transplant, Jackie Hannah secretly arranged for a ceremony for her husband David and her to renew their marriage vows. While he was in the Bone Marrow Transplant Unit in March, just after the transplant, and still dressed in his pajamas, David married Jackie again with hospital staff in attendance.

With ‘new life’ after transplant, cancer survivor renews marriage vows - Read More…

Black, white men view impacts of prostate cancer treatment differently, study finds

Black, white men view impacts of prostate cancer treatment differently, study finds

UNC Lineberger researchers led by Ronald C. Chen surveyed 1,171 men diagnosed with prostate cancer in North Carolina, finding that while both white and black men were concerned about curing their cancer and the quality-of-life impacts of treatment, more black men considered other social and personal factors -- such as recovery time and cost -- to be very important in their treatment decision-making.

Black, white men view impacts of prostate cancer treatment differently, study finds - Read More…

 Payments linked to higher odds of doctors prescribing certain cancer drugs

Payments linked to higher odds of doctors prescribing certain cancer drugs

In preliminary findings that will be presented at the American Society of Clinical Oncology Annual Meeting 2017 in Chicago on Saturday, June 3, researchers show that when physicians had to choose between multiple, on-patent drugs for metastatic kidney cancer and chronic myeloid leukemia, they were more likely to prescribe drugs from companies they had received general payments from.

Payments linked to higher odds of doctors prescribing certain cancer drugs - Read More…

Researchers continue to seek strategy for starving brain tumors

Researchers continue to seek strategy for starving brain tumors

In the journal Cancer Research, UNC Lineberger researchers led by member Timothy R. Gershon, MD, PhD, report in the latest in a series of attempts to shut down the energy production machinery in medulloblastoma, the most common malignant brain tumor in children. The findings may help researchers identify a suitable therapeutic target within the sugar metabolism pathway, and provide clues to a scientific mystery surrounding the confounding way that some cancer cells get energy from sugar.

Researchers continue to seek strategy for starving brain tumors - Read More…

Study confirms link between alcohol consumption, breast cancer risk in black women

Study confirms link between alcohol consumption, breast cancer risk in black women

In findings published in the journal Cancer, Epidemiology, Biomarkers & Prevention, UNC Lineberger Comprehensive Cancer Center researchers confirmed the link between alcohol consumption and breast cancer risk in a study in black women. The association has been seen in other studies drawn from majority white populations.

Study confirms link between alcohol consumption, breast cancer risk in black women - Read More…