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Approval Processes for Clinical Practice Guidelines Introduce Potential Conflicts of Interest, Review Finds

Approval Processes for Clinical Practice Guidelines Introduce Potential Conflicts of Interest, Review Finds

The study led by UNC’s Jeffrey Sonis, MD, MPH, in the departments of social medicine and family medicine, finds that most of the approval processes used by medical specialty societies in the U.S. have the potential to undermine editorial independence of the guideline development committee.

Approval Processes for Clinical Practice Guidelines Introduce Potential Conflicts of Interest, Review Finds - Read More…

A New Jetlag Drug? Scientists Create Selective Molecules to Bind to Melatonin Receptors

A New Jetlag Drug? Scientists Create Selective Molecules to Bind to Melatonin Receptors

Researchers from the UNC School of Medicine, UC San Francisco, and the University of Buffalo used 3-D computer simulations and pharmacological experiments to create molecules that selectively target the MT1 melatonin receptor to modulate the biological clocks in animal models of jet lag. Bryan L. Roth, MD, PhD, is co-senior author.

A New Jetlag Drug? Scientists Create Selective Molecules to Bind to Melatonin Receptors - Read More…

UNC School of Medicine Announces New Class of FIRST Scholars

UNC School of Medicine Announces New Class of FIRST Scholars

The Fully Integrated Readiness for Service Training (FIRST) is a three-year medical school curriculum to fast-track UNC School of Medicine students into UNC Family Medicine Residency, followed by three years of service in NC with ongoing support in practice.

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Key Molecular Machine in Cells Pictured in Detail for the First Time

Key Molecular Machine in Cells Pictured in Detail for the First Time

Histone mRNA-cleaving machine, crucial for healthy cell division, yields up its secrets after almost half a century of research. Zbigniew Dominski, PhD, and William Marzluff, PhD, led this effort at the UNC School of Medicine, along with key collaborators at Columbia University and Rockefeller University.

Key Molecular Machine in Cells Pictured in Detail for the First Time - Read More…

Researchers develop method to engineer immune cells so they grow even in hostile tumors

Researchers develop method to engineer immune cells so they grow even in hostile tumors

Researchers led by UNC Lineberger’s Gianpietro Dotti, MD, report in the journal Nature Biotechnology they have created a method for providing a stimulatory signal to super-charge cancer-hunting immune cells, called chimeric antigen receptor T-cells, that have been genetically engineered to hunt and kill specific cancers.

Researchers develop method to engineer immune cells so they grow even in hostile tumors - Read More…

Study finds blood test accurately tracks HPV-linked head and neck cancer

Study finds blood test accurately tracks HPV-linked head and neck cancer

Bhisham Chera, MD, and Gaorav Gupta, MD, PhD, led a study of a blood test to accurately detect HPV-linked head and neck cancer recurrence and confirm when there was no evidence of disease.

Study finds blood test accurately tracks HPV-linked head and neck cancer - Read More…

Nyrop Receives Grant to Study Interventions for Racial Disparities in Breast Cancer Survival

Nyrop Receives Grant to Study Interventions for Racial Disparities in Breast Cancer Survival

Kirsten Nyrop, PhD, UNC Lineberger member and assistant professor of hematology/oncology, has received a $50,000 award from the Integrated Approach to Breast Health Equity Competitive Grant Program, a collaboration between the American Cancer Society and Pfizer.

Nyrop Receives Grant to Study Interventions for Racial Disparities in Breast Cancer Survival - Read More…

FDA approves first drug for treatment of peanut allergy for children

FDA approves first drug for treatment of peanut allergy for children

This new treatment was developed after years of research, much of it spearheaded and completed by Wesley Burks, MD, and Edwin Kim, MD at the UNC School of Medicine.

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Silverstein celebrates five years as a ‘previvor’ with UNC Lineberger fundraiser

Silverstein celebrates five years as a ‘previvor’ with UNC Lineberger fundraiser

After consulting with an interdisciplinary team of “angel doctors” from the University of North Carolina Lineberger Comprehensive Cancer Center, Charlotte resident Beth Silverstein made a series of health decisions that changed her life.

Silverstein celebrates five years as a ‘previvor’ with UNC Lineberger fundraiser - Read More…

NCI Appoints Gopal Director of Center for Global Health

NCI Appoints Gopal Director of Center for Global Health

The National Cancer Institute has named Satish Gopal, MD, MPH, director of the NCI Center for Global Health. He began this his new role February 3, 2020.

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UCLA, UNC, MIT Researchers Successfully Test Coin-Sized Smart Insulin Patch

UCLA, UNC, MIT Researchers Successfully Test Coin-Sized Smart Insulin Patch

Zhen Gu, PhD, former professor in the UNC/NSCU Joint Department of Biomedical Engineering, led animal studies, a precursor to human trials, for a new device to automatically manage glucose levels and deliver needed insulin quickly. UNC’s John Buse, MD, PhD, was co-author of the study.

UCLA, UNC, MIT Researchers Successfully Test Coin-Sized Smart Insulin Patch - Read More…

UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells

UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells

Researchers led by UNC Lineberger’s Gianpietro Dotti, MD, reported new findings about the regulation of co-stimulatory molecules that could be used to activate cancer-killing immune cells – chimeric antigen receptor T-cells, or CAR-T. The molecules could also be used to decrease the activity of these cells.

UNC Lineberger discovery would allow researchers to fine-tune activity of cancer-hunting immune cells - Read More…

UNC Health Care Expands Services Available for Children in Wake County

UNC Health Care Expands Services Available for Children in Wake County

UNC Children’s Raleigh clinic and a new pediatrics wing at UNC REX Hospital will improve care for kids.

UNC Health Care Expands Services Available for Children in Wake County - Read More…

Researchers Reverse HIV Latency, Important Scientific Step Toward Cure

Researchers Reverse HIV Latency, Important Scientific Step Toward Cure

Overcoming HIV latency – induction of HIV in CD4+ T cells that lay dormant throughout the body – is a major step toward creating a cure for HIV. For the first time, scientists at UNC-Chapel Hill, Emory University, and Qura Therapeutics – a partnership between UNC and ViiV Healthcare – have shown that a new approach can expose latent HIV to attack in two different animal model systems with little or no toxicity.

Researchers Reverse HIV Latency, Important Scientific Step Toward Cure - Read More…

Improving Cardiovascular Health of the Most Vulnerable

Improving Cardiovascular Health of the Most Vulnerable

Heart disease and stroke are major causes of pre-mature mortality and morbidity in North Carolina, and there are significant racial and geographic disparities in cardiovascular care, morbidity and mortality. A two-year pilot project led by Rick Stouffer, MD, shows how the cardiovascular health of the most vulnerable patients can be improved with free medications.

Improving Cardiovascular Health of the Most Vulnerable - Read More…

Remembering Dr. Jeffrey Houpt

Remembering Dr. Jeffrey Houpt

Jeffrey L. Houpt, MD, Dean Emeritus of the UNC School of Medicine, and former CEO of UNC Health Care, passed away on January 13 at the age of 78.

Remembering Dr. Jeffrey Houpt - Read More…

Katrina Donahue, MD, MPH, Appointed to the U.S. Preventive Services Task Force

Katrina Donahue, MD, MPH, Appointed to the U.S. Preventive Services Task Force

UNC Department of Family Medicine professor and vice chair of research, Katrina Donahue MD, MPH, has been appointed to the U.S. Preventive Services Task Force as one of its newest members.

Katrina Donahue, MD, MPH, Appointed to the U.S. Preventive Services Task Force - Read More…

Researchers find clues to drug resistance in medulloblastoma subtype

Researchers find clues to drug resistance in medulloblastoma subtype

University of North Carolina Lineberger Comprehensive Cancer Center researchers led by Timothy Gershon, MD, PhD, and Kirk Wilhelmsen, MD, PhD, have new evidence to explain how drug resistance develops in a major subtype of medulloblastoma, the most common invasive brain tumor in children.

Researchers find clues to drug resistance in medulloblastoma subtype - Read More…

A Full Breakdown of All Vaping Industry Academic Scholarships to High Schoolers

A Full Breakdown of All Vaping Industry Academic Scholarships to High Schoolers

Led by Adam Goldstein, MD, UNC Family Medicine researchers published details on how electronic cigarette companies offer academic scholarships to high school-age teenagers and young adults, showing a disconnect between the industry’s desire to increase vaping among young people and the desire of health advocates to decrease such usage.

A Full Breakdown of All Vaping Industry Academic Scholarships to High Schoolers - Read More…

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